This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
Children who walk to school less likely to ... Children who regularly walk or cycle to school are less likely ... (20 May 2019)
Women with sleep apnoea are more likely to ... A study of more than 19,000 people has found that women with ... (20 May 2019)
Passion trumps love for sex in relationships When women distinguish between sex and the relational and ... (17 May 2019)
Inflammatory Bowel Disease During Childhood ... A new study revealed an increased risk of cancer and early death ... (13 May 2019)
Fracture Risk Tool Is Useful in Women with ... The FRAX®tool takes into account certain factors to determine ... (13 May 2019)
Wednesday, 21 November 2018 19:37

Probiotic No Better Than Placebo for Acute Gastroenteritis in Children Featured

Rate this item
(0 votes)

While probiotics are often used to treat acute gastroenteritis in children, the latest evidence shows no significant differences in outcomes, compared to a placebo. These results come from the large, double-blind, randomized controlled trial conducted at 10 geographically diverse U.S. pediatric emergency departments. Findings were published in the New England Journal of Medicine.

“This study presents the most robust evidence to date that use of probiotics does not improve outcomes of acute gastroenteritis in children, which calls into question current recommendations,” says author Elizabeth Powell, MD, MPH, pediatric emergency medicine specialist at Lurie Children’s and Professor of Pediatrics at Northwestern University Feinberg School of Medicine. “Recommendations to use probiotics for these patients were based on previous meta-analyses that have suggested probiotics may be beneficial, but the trials that were included had significant limitations. The rigor of our research design and our results warrant reconsideration of common practice.”

Acute gastroenteritis, which can present with diarrhea, vomiting and abdominal pain is the second leading cause of death worldwide in children younger than 5 years.

The study included 943 children, aged 3 months to 4 years of age. Two weeks after an emergency department visit for acute gastroenteritis, children in the study who received a five-day course of probiotic (Lactobacillus rhamnosus) fared no better than the placebo group in terms of illness severity, duration and frequency of diarrhea or vomiting, day-care absenteeism and rate of household transmission of the infection.



Source Newsroom: Ann and Robert H. Lurie Children's Hospital of Chicago

Read 494 times Last modified on Wednesday, 21 November 2018 19:53

Latest news

Highlights

Join

Connect with other Medical Professionals on fb in a closed facebook group

Login

Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…