This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
On World Arthritis Day ‘Don’t Delay, Connect ... On World Arthritis Day ‘Don’t Delay, Connect Today’ Campaign ... (15 Oct 2018)
3D mammography detected 34% more breast ... “With breast tomosynthesis, 34 per cent more cancer tumours were ... (15 Oct 2018)
Breastfeeding protects infants from ...  A new study from the University of Helsinki shows that babies ... (15 Oct 2018)
Reduced risk of severe stroke for ... Physical activity not only reduces the risk of stroke. ... (15 Oct 2018)
Link between Gut Flora and Multiple ...  In multiple sclerosis, a defective response of the body’s own ... (15 Oct 2018)
Sunday, 07 October 2018 19:17

Teen cannabis use is not without risk to cognitive development Featured

Rate this item
(0 votes)

Although studies have shown that alcohol and cannabis misuse are related to impaired cognition in youth, previous studies were not designed to understand this relationship and differentiate whether cannabis use was causal or consequential to cognitive impairment. A new study by researchers at CHU Sainte-Justine and Université de Montréal, published in the American Journal of Psychiatry,shows that beyond the role of cognition in vulnerability to substance use, the concurrent and lasting effects of adolescent cannabis use can be observed on important cognitive functions and appear to be more pronounced than those observed for alcohol.

Beyond acute intoxicating effects, alcohol and cannabis misuse has been associated with impairments in learning, memory, attention and decision-making, as well as with lower academic performance. “While many studies have reported group differences in cognitive performance between young users and non-users, what had yet to be established was the causal and lasting effects of teen substance use on cognitive development,” said co-author and PhD student at Université de Montréal,Jean-François G. Morin. Senior author and investigator Dr. Patricia Conrod, from the Department of Psychiatry at Université de Montréal, added that “very few studies are designed to look at this question from a developmental perspective. Our study is unique in that it followed a large sample of high school students from 7th to 10th grade using cognitive and substance-use measures. Using this big-data approach, we were able to model the complex nature of the relationship between these sets of variables.”

To understand the relationship between alcohol, cannabis use and cognitive development among adolescents at all levels of consumption (abstinent, occasional consumer or high consumer), the research team followed a sample of 3,826 Canadian adolescents over a period of four years. Using a developmentally sensitive design, the authors investigated relationships between year-to-year changes in substance use and cognitive development across a number of cognitive domains, such as recall memory, perceptual reasoning, inhibition and working memory. Multi-level regression models were used to simultaneously test vulnerability and concurrent and lasting effects on each cognitive domain. The study found that vulnerability to cannabis and alcohol use in adolescence was associated with generally lower performance on all cognitive domains.

“However, further increases in cannabis use,but not alcohol consumption, showed additional concurrent and lagged effects on cognitive functions, such as perceptual reasoning, memory recall, working memory and inhibitory control,” Conrod said. “Of particular concern was the finding that cannabis use was associated with lasting effects on a measure of inhibitory control, which is a risk factor for other addictive behaviours, and might explain why early onset cannabis use is a risk factor for other addictions.” Morin added: “Some of these effects are even more pronounced when consumption begins earlier in adolescence.”

In a context where policies and attitudes regarding substance use are being reconsidered, this research highlights the importance of protecting youth from the adverse effects of consumption through greater investment in drug-prevention programs.

“It will be important to conduct similar analyses with this cohort or similar cohorts as they transition to young adulthood, when alcohol and cannabis use become more severe,” Conrod said. “This might be particularly relevant for alcohol effects: while this study did not detect effects of teen alcohol consumption on cognitive development, the neurotoxic effects may be observable in specific subgroups differentiated based on the level of consumption, gender or age.” Morin added: “We also want to identify if these effects on brain development are related to other difficulties such as poor academic performance, neuroanatomical damage, and the risk of future addiction or mental health disorders.”


Source: Université de Montréal
Full bibliographic information

The article entitled “A Population-Based Analysis of the Relationship between Substance Use and Adolescent Cognitive Development” was published in the American Journal of Psychiatry in October 2018.

Read 76 times Last modified on Tuesday, 09 October 2018 10:18

TheSynapse Videos

0
0
0
0
0
0

Latest news

Highlights

  • Les Laboratoires Servier - Job Vacancy
    Written on June 29, 2018 Read more...
  • Interactive Discussion on Valsartan

     

     

    The Malta Medicines Authority in collaboration with the Superintendence
    of Public Health and the Department of Pharmacy University of Malta
    would like to cordially invite you to an interactive scientific discussion:

     

     


    THE VALSARTAN SAGA


    SCIENCE | MYTHS | REALITIES

     


    led by Professor Anthony Serracino Inglott

     


    Date: Wednesday 25 July 2018

     


    Time: 20:00
    Venue: Conference Room, Life Sciences Park, San Ġwann

     


    Refreshments will be served


    RSVP: info.medicinesauthority@gov.mt | 23439202

    Written on July 21, 2018

Join

Connect with other Medical Professionals on fb in a closed facebook group

captcha  

Login

Template Settings

Theme Colors

Cyan Red Green Oranges Teal

Layout

Wide Boxed Framed Rounded
Patterns for Layour: Boxed, Framed, Rounded
Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…