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Saturday, 21 April 2018 09:35

Has aspirin an indication in grief? Featured

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An investigation that has appeared in the current issue of Psychotherapy and Psychosomatics suggests that low-dose aspirin may have a role in the prevention of cardiovascular risk associated with bereavement.

In the 24 h following the death of a significant person, the incidence of acute myocardial infarction increases 21.1-fold. Low-dose aspirin could be a suitable prevention strategy in acute bereavement.

To investigate aspirin as a feasible preventive intervention, acutely bereaved participants (n = 10) were recruited on average within 30 days (SD = 14.67) of the death of their spouse along with nonbereaved controls (n = 12). Hemodynamic markers (blood pressure, heart rate, HRV) and depressive symptoms (Center for Epidemiologic Studies Depression Scale; CES-D) were assessed during 2 laboratory visits. Results show an attenuated physiological reactivity to a grief-related stress task and a beneficial effect on depressive symptoms in the aspirin group. Higher cardiovascular reactivity to emotional stressors in bereavement could amplify increased cardiovascular risk. The effect of aspirin on depressive symptoms is consistent with previous studies linking depressive symptoms with inflammation.

In conclusion, aspirin may have a potential preventive benefit targeting increased cardiovascular risk in bereavement. Further research is needed to investigate this potential link.


Source: Journal of Psychotherapy and Psychosomatics

Full bibliographic information

Low-Dose Aspirin for Prevention of Cardiovascular Risk in Bereavement: Results from a Feasibility Study. Psychother Psychosom 2018;87:112–113

Read 264 times Last modified on Saturday, 21 April 2018 11:00

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    The Malta Medicines Authority in collaboration with the Superintendence
    of Public Health and the Department of Pharmacy University of Malta
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    THE VALSARTAN SAGA


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    led by Professor Anthony Serracino Inglott

     


    Date: Wednesday 25 July 2018

     


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    Refreshments will be served


    RSVP: info.medicinesauthority@gov.mt | 23439202

    Written on July 21, 2018

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