This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
The more you smoke, the greater your risk of ... The more you smoke, the greater your risk of atrial ... (17 Jul 2018)
New Cochrane health evidence challenges ... New evidence shows there is little or no effect of omega 3 ... (17 Jul 2018)
Weight Loss Surgery May Affect the Risk of ... A new analysis published in the BJS(British Journal of Surgery) ... (17 Jul 2018)
15-minutes of exercise creates optimal brain ... Exercise increases brain connectivity and efficiency If you ... (13 Jul 2018)
Valsartan: Updated list of potentially ... The Superintendent of Public Health has issued an updated list ... (13 Jul 2018)
Monday, 29 August 2016 00:00

Update on Avian Influenza

Written by
Rate this item
(0 votes)

by Tanya Melillo Fenech MD MSc
Principle Medical Officer at Infectious Disease Prevention and Control Unit
Department of Health Promotion and Disease Prevention

Study on environmental sampling during an Avian Outbreak in Cambodia

Samples were taken from the environment of households within one kilometre of the confirmed outbreak of birds or confirmed human cases. They sampled mud, still water (ponds), soil and water plants in and around 14 households areas in three villages with PCR testing. Viral RNA was detectable in poultry faeces, soil, some unconcentrated water, mud, water plants and feathers of dead poultry. However it was not possible to isolate any viruses so the role of environmental contaminants in infecting humans is so far still unclear. However it does reinforce the theory that those in contact with poultry and their detritus are at a potential risk of avian influenza and other zoonotic infections.

Update on Oseltamivir resistance in 2007-2008 seasonal influenza viruses in Europe

Although sporadic low level transmission of drug resistant viruses has  taken place since 1999 when the Neuraminidase inhibitor drugs were first licensed, it was the winter season 07/08 that for the first time showed widespread and sustained transmission of such viruses in the community. Such viruses previously had not been able to readily transmit and had rapidly disappeared.

The proportion of Influenza A (H1N1) viruses that were found to be oseltamivir resistant varied significantly across Europe. The highest proportion of resistant viruses to date has been in Norway followed by Belgium, France, Netherlands and Luxembourg. Surveillance in previous years by the Virgil Project found <1% of circulating viruses to be resistant. There is no evidence that the appearance of these new viruses are related to use of oseltamivir which is currently not widely prescribed in most European countries. The European Centre of Disease Prevention and Control (ECDC) is now working with the manufacturer and national authorities to gather more information on routine oseltamivir use in Europe.

The clinical experience in Norway and elsewhere suggests that people who become ill with an oseltamivir resistant strain of Influenza A(H1N1) had a similar spectrum of illness to those infected with ‘normal’ seasonal influenza A, which can cause severe disease or death in vulnerable people (older people, those with debilitating illnesses and the very young).

At this stage the significance of these findings remains uncertain. The emergence of drug resistance in the context of limited drug use is unexpected, and the extent of future circulation is difficult to predict. The ECDC, WHO, European Influenza Surveillance Scheme (EISS), European Surveillance Network for Vigilance against Viral Resistance (VIRGIL) and authorities in the member states are undertaking intensive surveillance to monitor this.

Additional Info

  • TheSynapse Magazines: 2008
Read 2315 times Last modified on Saturday, 19 November 2016 23:23

TheSynapse Videos

0
0
0
0
0
0

Highlights

  • Les Laboratoires Servier - Job Vacancy
    Written on June 29, 2018 Read more...
  • WASP Course in Bahrain

    WASP Course, led by Prof Victor Grech and Prof Charles Savona Ventura, has recently organised a course in Bahrain. Co-hosted with Arabian Gulf University, the course, on how to write a scientific paper, focused on quantitative analysis methods and was targeted for medical doctors and allied health professionals.

    Written on April 24, 2018 Read more...

Join

Connect with other Medical Professionals on fb in a closed facebook group

captcha  

Login

Template Settings

Theme Colors

Cyan Red Green Oranges Teal

Layout

Wide Boxed Framed Rounded
Patterns for Layour: Boxed, Framed, Rounded
Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…