This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
On World Arthritis Day ‘Don’t Delay, Connect ... On World Arthritis Day ‘Don’t Delay, Connect Today’ Campaign ... (15 Oct 2018)
3D mammography detected 34% more breast ... “With breast tomosynthesis, 34 per cent more cancer tumours were ... (15 Oct 2018)
Breastfeeding protects infants from ...  A new study from the University of Helsinki shows that babies ... (15 Oct 2018)
Reduced risk of severe stroke for ... Physical activity not only reduces the risk of stroke. ... (15 Oct 2018)
Link between Gut Flora and Multiple ...  In multiple sclerosis, a defective response of the body’s own ... (15 Oct 2018)
Friday, 10 November 2017 22:52

Neutrophilic dermatosis of the dorsal hands

Written by
Rate this item
(0 votes)

D Micallef, M Bonnici, *D Pisani, D Mintoff, *O Woods, M J Boffa; Department of Dermatology, Sir Paul Boffa Hospital, Malta & *Department of Pathology, Mater Dei Hospital, Malta

Neutrophilic dermatosis of the dorsal hands (NDDH) is an uncommon localised variant of Sweet syndrome characterised by tender erythematous plaques, pustules and bullae on the dorsae of the hands. In this presentation we report three new cases of NDDH in Malta. All patients were female, aged 60-82 years and presented with ulcerated violaceous plaques on the dorsae of the hands. The diagnosis was confirmed histologically in each case. Neutrophil leucocytosis was noted in all cases and two had raised inflammatory markers. None of the cases were associated with inflammatory diseases or malignancy and all resolved with corticosteroids. We performed a comprehensive literature review and found 94 cases of NDDH reported on PubMed. The mean patient age was 59 years and 60.5% were females. 84.0% of cases had reported bilateral involvement and other sites were affected in 31.9%. Underlying disease was found in a significant proportion, notably 13 cases of recent infection, 11 cases of haematological disorders (myeloproliferative disorders, myelodysplasia, or malignancies), 9 cases of active solid organ tumours and 3 patients with inflammatory bowel disease. Systemic and/or topical corticosteroids were employed in the treatment of 77.7% of cases while dapsone and colchicine were the commonest steroid-sparing agents used. All treatment regimens led to improvement which was often rapid and complete. While NDDH is uncommon, the fact that three cases were encountered locally over five years raises the possibility that the condition might actually be commoner than thought and may be misdiagnosed. Awareness of NDDH is important since a correct diagnosis would trigger a search for underlying diseases and proper treatment with corticosteroids and/or steroid-sparing agents.

 

Click here to download the programme and register to attend Dermfest 2017

Read 1673 times

TheSynapse Videos

0
0
0
0
0
0

Jamesco News

Has no content to show!

GSK

Vivian

TheSynapse Magazines

Latest news

Highlights

  • WASP Course in Bahrain

    WASP Course, led by Prof Victor Grech and Prof Charles Savona Ventura, has recently organised a course in Bahrain. Co-hosted with Arabian Gulf University, the course, on how to write a scientific paper, focused on quantitative analysis methods and was targeted for medical doctors and allied health professionals.

    Written on April 24, 2018 Read more...
  • Interactive Discussion on Valsartan

     

     

    The Malta Medicines Authority in collaboration with the Superintendence
    of Public Health and the Department of Pharmacy University of Malta
    would like to cordially invite you to an interactive scientific discussion:

     

     


    THE VALSARTAN SAGA


    SCIENCE | MYTHS | REALITIES

     


    led by Professor Anthony Serracino Inglott

     


    Date: Wednesday 25 July 2018

     


    Time: 20:00
    Venue: Conference Room, Life Sciences Park, San Ġwann

     


    Refreshments will be served


    RSVP: info.medicinesauthority@gov.mt | 23439202

    Written on July 21, 2018

Join

Connect with other Medical Professionals on fb in a closed facebook group

captcha  

Login

Template Settings

Theme Colors

Cyan Red Green Oranges Teal

Layout

Wide Boxed Framed Rounded
Patterns for Layour: Boxed, Framed, Rounded
Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…